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Pimozide is used to treat motor and verbal tics in people who have not adequately responded to, or cannot take, other medications to treat Tourette syndrome.

This is accounted for by the possible differences in their inactive ingredients such as color and flavor additives, and by the copyright and trademark regulations that does not allow for exact copies of the existing brand-name products.

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They stated that the results of this first meta-analysis were encouraging, and further studies are needed to detail efficacy in bipolar disorders and other specific depressed populations; middle- and long-term safety and effectiveness have yet to be explored.

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Pimozide works in the central nervous system to help control the vocal outbursts and uncontrolled, repeated movements of the body (tics) that may interfere with the patient's normal life.

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This meta-analysis found that the combination of anti-psychotic medications and ECT could improve psychiatric symptoms in patients with refractory schizophrenia, but the incomplete methodological information provided for most of the studies, publication bias (favoring studies with better outcomes in the combined treatment group), and the low quality of evidence about adverse outcomes, cognitive impairment, and overall functioning raised questions about the validity of the results.

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Persecutory delusions involve conspiracy against or mistreatment of the patient.

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